Cholesterol activates the G-protein coupled receptor Smoothened to promote morphogenetic signaling

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http://biorxiv.org/content/early/2016/08/21/070623

Giovanni Luchetti, Ria Sircar, Jennifer H Kong, Sigrid Nachtergaele, Andreas Sagner, Eamon FX Byrne, Douglas F Covey, Christian Siebold, Rajat Rohatgi

Preprint journal club review posted to The Winnower: review

-Wei Wang and Cassi Johnson, University of Kansas Medical Center, Interdisciplinary Graduate Program in Biomedical Sciences

 

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